A Typical Response to Fertility Medications?

A patient's response to fertility medications depends on her number of available eggs (ovarian reserve), appropriate hormone levels, and the proper administration of medications. If a woman has a diminished ovarian reserve high follicle stimulating hormone (FSH), low anti-mullerian hormone (AMH) and low antral follicle count (AFC), she may not respond as well as others might to her stimulating medications.  For these women, an alternate protocol, multiple retrievals or donated eggs may be useful. 

In some cases, women have a good ovarian reserve but do not produce the pituitary hormone FSH to stimulate follicular growth. Administration of a medication that contains FSH and LH may allow for an optimal response. 

Lifestyle factors such as obesity, smoking or being under-weight can also affect one's ovarian response to fertility medications.  Optimizing weight and reducing smoking and alcohol use can improve ovarian stimulation.  Additional treatment for a patient with a low response would be the use of advanced laboratory techniques that can include assisted hatching and/or a day 2 or 3 embryo transfer.